HOMEWORK

1. What are ribonucleotide reductases and describe their three classes with their characteristics?
2. Explain the synthesis of thymine from dUMP catalyzed by thymidylate synthase?
3. Discuss the formation of uric acid from purine catabolism with the substrates and their respective enzymes?
4. How different animals degrade uric acid and explain the various products from these animals? How pyrimidines are degraded to malonyl-CoA and methylmalonyl-CoA?
5. What is gout? Discuss its symptoms with treatment regimens?