What percentage of the base pairs are altered each day?

Description/explanation of possible solutions, (c) Use/understanding of core class concepts, (d) Integration of multiple concepts from the class, and (e) Use of correct grammar, spelling and composition conventions
June 20, 2018
What type of aneuploidy is exhibited? (monosomic, disomic, trisomic, etc.) What conditions are associated with this type of aneuploidy? Which chromosomes are impacted?
June 20, 2018

What percentage of the base pairs are altered each day?

Problem Set 6 – Problems on Gene Expression/Repair and Protein Synthesis/Degradation (3

problems):

16. The DNA in a human non-gametic cell contains 6 billion base pairs. It is estimated that

about 10,000 DNA changes occur in each cell in one day. These are quickly repaired so that

only a few (1 to 5) mutations accumulate in one cell in a year.

a. What percentage of the base pairs are altered each day?

b. What percentage of the DNA changes that occur in one cell in one year escape

the proofreading and repair process – calculate this in both cases: if 1 mutation

accumulates in one cell per year, and if 5 mutations accumulate in one cell per

year?