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What specific processes do anesthetics impair and how does this interfere with nerve transmission?

Biology Anatomy and PhysiologyProject descriptionPlease include a cover page and reference page.1. When a suicide victim was found the coroner was unable to remove the drug vial clutched in his hand. Explain the reasons for this. If the victim had been discovered three days later would the coroner have had the same difficulty? Explain.2. General and local anesthetics block action potential generation thereby rendering the nervous system inactive while surgery is performed. What specific processes do anesthetics impair and how does this interfere with nerve transmission?3. Explain the link between acetylcholine and Alzheimers disease.4. You have been hired by a pharmaceutical company to develop a drug to regulate a specific brain disorder. What is a major physiological roadblock to developing such a drug and how can you design a drug to bypass that roadblock so that the drug is delivered to the brain where it is needed?

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