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Below is a copy of Quiz 2 (25 points). Read carefully and answer the questions. This is an open book quiz, however, you are expected to do your own work and for the short answer questions write the answers using your own words. Submit as a Word or rtf attachment (please put your last name in the file name of attached documents–for example student John Smith would be Smith J.Quiz 2. doc). Your completed quiz is due no later than 11:59 P.M. Eastern Time, June 02, 2020. See the syllabus for the policy on late submissions.
Part A. Fill in the blank
- (1 point) You are given a nucleic acid sample with the following sequence:
AUGGCGGGUGUACUAUAG. Is the sample RNA or DNA and how do you know? - (1 point) The three- letter mRNA nucleotide sequence that specifies an amino acid is called a _.
- (2 points) Describe what would happen if GGU in mRNA is changed to GGA. Name the type of mutation and describe its effect on the primary structure (amino acid sequence) of the polypeptide __________
- (2 points) Describe what would happen if GGU in mRNA is changed to GUU. Name the type of mutation and describe its effect on the primary structure (amino acid sequence) of the polypeptide __________
Types and effects of DNA mutations are described in Course Module 2 Commentary. A Genetic Decoder Table is posted in Week 2 topic Key Concept: DNA, RNA & the Genetic Code
Part B. Short answers
See the Syllabus for links to tutorials and examples of how to avoid plagiarism and to write in your own words.
Important: You must include a complete citation in APA style for the source(s) of information you used to answer questions 7-10, or that support your answer. If you include complete citations at the end of the quiz, then you need to include in-text citations within your answers. See UMUC Library for citation examples and tutorials (Resources > Library > Get Help > Citing and Writing). Some unacceptable sources: Wikipedia, Yahoo Answers and similar type websites; also see Announcement: An important message about tutoring services at UMUC and online cheating. Points will be deducted for incomplete citations and no points will be earned for answers without sources cited or incorrect sources cited. - (3 points) What role do the existing strands of DNA play during the synthesis of the new DNA strands? Use the following sequence of double stranded DNA to illustrate how the existing and new strands are related after replication of the molecule (label which are the new and old strands).
3ʹ-TACCGCCCACATATC-5ʹ
5ʹ-ATGGCGGGTGTATAG-3ʹ
- (3 points) RNA is synthesized on a DNA template in a process called _ which utilizes the enzyme _. Describe the events and molecules involved in this process. Use the DNA molecule in question 5 to illustrate and show the RNA product. [Hint: The template strand for transcription: 3ʹ-TACCGCCCACATATC-5ʹ
Important Note: The RNA sequence in Module 2 Commentary Animation 2.2 is incorrect (see correct sequence in week 2 key concept topic DNA, RNA & the Genetic Code)
- (3 points) Proteins are synthesized using mRNA as a template in a process called _. Illustrate and show the amino acid sequence for the mRNA sequence you determined in question 6.
- (3 points) Describe at least three functions of cell membranes.
- (4 points) In a table compare general structural similarities between prokaryotic and eukaryotic cells related to genetic organization, compartmentation, protein synthesis, and cell motility.
- (3 points) What are the three major types of RNA molecules involved in protein synthesis and their function?
Sample Solution
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